Michael Kurilla, M.D., Ph.D., NCATS Director of the Division of Clinical Innovation, writes a monthly blog on a wide variety of topics relevant to the CTSA Program. Mike’s Blog is featured each month in the Ansible, the CTSA Program newsletter.
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June 3, 2026
Let’s Get Real: Rigorous and Reproducible RWD Research that Benefits All
Translating discoveries from early human trials into effective real-world health solutions is central to the CTSA Program mission. As translational science continues to evolve, rigor and reproducibility remain essential research pillars. Real-world data (RWD) and the resulting real-world evidence (RWE) are increasingly important for advancing research across the translational spectrum,...
By: Pablo Cure, Jamie Doyle, Gallya Gannot, & Christopher Hartshorn
May 6, 2026
Is Anyone Really Surprised?
A recent Stat article highlighted early results from the CMS’ WISeR (Wasteful and Inappropriate Service Reduction) Model, an AI-enabled prior authorization pilot now underway in six states. The program is being piloted in Arizona, New Jersey, Oklahoma, Ohio, Texas, and Washington, which includes ten CTSAs. The...
By: Michael Kurilla, M.D., Ph.D., NCATS Director of the Division of Clinical Innovation
March 30, 2026
When the Fecal Matter Hits the Circulating Blade; Just a ‘Gut’ Feeling
One advantage of a long career in medicine is the opportunity to witness the emergence and development of new concepts that advance from curious observations to routine clinical practice. One area of growing interest is the microbiome and its potential for manipulation. Its reach now appears far broader than we...
By: Michael Kurilla, M.D., Ph.D., NCATS Director of the Division of Clinical Innovation
March 2, 2026
Odds and Ends
Gotta admit, the groundhog was right this year. DC is digging out of its second snowfall of the year. Typically, we get at most one snow event where enough snow falls and sticks around to impact the area. This latest was smaller than the previous but still closed schools and...
By: Michael Kurilla, M.D., Ph.D., NCATS Director of the Division of Clinical Innovation
February 2, 2026
Can't Seem to Stop the Stuttering
I’m writing this blog entry in the waning days of the current continuing resolution (CR) we are operating under which expires as of Friday (January 30) at midnight (technically Saturday, January 31 at 12:01AM). Things had been looking quite hopeful over the last several weeks. The USG funds itself with...
By: Michael Kurilla, M.D., Ph.D., NCATS Director of the Division of Clinical Innovation



