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Goal #4: Improve clinical research

An SC CTSI-supported study could help improve prescribing guidance for surgeons, increasing chances that adolescent patients receive an appropriate amount of pain medication after procedures.&nbsp;Providers caring for teens after surgery may misjudge how many opioid pills are needed, sometimes prescribing more or fewer than necessary. Prescribing too few opioid pills can offer too little pain relief. However, prescribing too many pills can raise concerns about addiction and safety of having unused opioids in the home…&nbsp;<a href="https://sc-ctsi.org/news/gaps-in-teen-opioid-prescriptions-after-surgery-reveal-a-path-forward" target="_blank" rel="noopener noreferrer">Read the full article.</a>

Southern California Clinical and Translational Science Institute

News graphic about gaps in teen opioid prescriptions after surgery, featuring a quote from Dr. Lorraine Kelley-Quon, a photo of white pills within a red circle, and the SC CTSI logo. Two teens are seated and talking in the background.

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University of Southern California

Gaps in Teen Opioid Prescriptions After Surgery Reveal a Path Forward

Goal #2: Promote partnerships and collaborations

Believe — seven-letter word that means far more than its dictionary definition for the Wackers, a family of six from Eureka, Missouri. In the four and half years since their eldest daughter Gianna was diagnosed with Sanfilippo syndrome, a terminal illness, “Believe” has become their family mantra — a testament of hope and joy that has spread beyond their home in Missouri and into the University of Iowa Clinical Research Unit…&nbsp;<a href="https://icts.uiowa.edu/news/2025/10/believe-how-one-girls-mantra-inspired-entire-care-team" target="_blank" rel="noopener noreferrer">Read the full article.</a>

University of Iowa Institute for Clinical and Translational Science

Gianna, and one of her Nurses Holly, smile with Nike shoes signed by the Iowa Football team 

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University of Iowa

How One Girl’s Mantra Inspired an Entire Care Team

CCTST K Scholar program graduate,&nbsp;<a href="https://www.cincinnatichildrens.org/bio/k/meera-kotagal" target="_blank" rel="noopener noreferrer">Meera Kotagal,&nbsp;M.D., M.P.H.</a>, associate professor in the Division of Pediatric General and Thoracic Surgery at Cincinnati Children’s, was recently awarded a K01 Mentored Research Scientist Career Development Award from the Center for Disease Control and Prevention&nbsp;(CDC).&nbsp;Dr. Kotagal’s project, titled&nbsp;“Use of System Dynamics Modeling and Human-Centered Design to Address Structural Drivers of Youth Firearm Violence,”&nbsp;aims to advance research on youth violence, with a particular focus on firearm-related injuries…&nbsp;<a href="https://www.cctst.org/post/k-scholar-program-graduate-kotagal-receives-funding-from-cdc" target="_blank" rel="noopener noreferrer">Read the full article.</a>

Cincinnati Center for Clinical and Translational Science and Training

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Cincinnati Children's Hospital Medical Center

K Scholar Program Graduate, Kotagal, Receives Funding From CDC

Goal #1: Advance clinical and translational science

Ryleigh Messmer is a 15-year-old from Colorado Springs who has cystic fibrosis (CF), a rare, life-shortening genetic disease that affects the lungs, pancreas, and other organs. When she was born, the only treatments to maintain lung health for people with CF were mucus clearance treatments to try to alleviate symptoms such as the buildup of thick, sticky mucus that would eventually damage the lungs.&nbsp;&nbsp;However, just two years later everything changed when the FDA approved ivacaftor, the first drug designed to target the defective protein that causes CF. This protein is called the cystic fibrosis transmembrane conductance regulator or CFTR. Much of the clinical research that ultimately led to the approval of ivacaftor, the first CFTR modulator, in 2012 took place at <a href="https://www.childrenscolorado.org/">Children’s Hospital Colorado</a> in collaboration with the <a href="https://cctsi.cuanschutz.edu/">Colorado Clinical and Translational Sciences Institute (CCTSI)</a>, which provides specialized research nursing, expert laboratory services and clinical space for the hundreds of children who participated in the research studies over the years…&nbsp; <a href="https://news.cuanschutz.edu/cctsi/cystic-fibrosis-research-reveals-new-insights" target="_blank" rel="noopener noreferrer">Read the full article.</a>

Colorado Clinical and Translational Sciences Institute

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University of Colorado Anschutz Medical Campus

Cystic Fibrosis Treatment Shows Long-Term Reduction in Inflammation 

A culture of multidisciplinary collaboration and teamwork is growing at the University at Buffalo (UB), and so, too, are the stories of successful grant submissions that have resulted from this emphasis on team science. To highlight this cross-disciplinary team approach to proposal development and offer guidance to researchers and research teams, the University at Buffalo Clinical and Translational Science (CTSI) <a href="https://www.buffalo.edu/ctsi/cores/workforce-development.html" target="_blank" rel="noopener noreferrer">Workforce Development Core</a> is sharing a series of interviews with veteran UB investigators.&nbsp;The ongoing series, titled “Behind the Proposal: Team Science and the Power of Cross-disciplinary Grant Collaboration,” is designed to gain unique insights from investigators who have productive and successful experience working in large interdisciplinary teams.&nbsp;<a href="https://www.buffalo.edu/ctsi/ctsi-news.host.html/content/shared/www/ctsi/articles/academic_articles/video-series-shares-team-science-insights.detail.html" target="_blank" rel="noopener noreferrer">Read the full article.</a>

University at Buffalo Clinical and Translational Science Institute

Four people paddling together in a long canoe, silhouetted against rippling water.

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Video Series Shares Team Science, Multidisciplinary Grant Collaboration Insights

<a href="https://engineering.washu.edu/faculty/Christine-OBrien.html">Christine O’Brien, Ph.D.</a>, an assistant professor of biomedical engineering at Washington University in St. Louis, was <a href="https://source.washu.edu/2025/09/tracking-deadly-and-unpredictable-postpartum-hemorrhage/?utm_source=newsletter&amp;utm_medium=email&amp;utm_content=Tracking%20deadly%20and%20unpredictable%20postpartum%20hemorrhage&amp;utm_campaign=Record%209-24-25">recently granted $2.8 million from the NIH</a> to develop a wearable device to track blood loss to prevent postpartum hemorrhage – the leading cause of maternal death worldwide.&nbsp;The goal is to design a wearable device that tracks blood loss through measuring cardiovascular features from a novel light-based sensor that measures changes in hemoglobin and blood flow. The team proposes that this wearable device could serve as a more accurate and continuous early warning system that could potentially prevent 50% to 90% of those maternal deaths from hemorrhage when paired with adequate treatment.&nbsp;<a href="https://icts.wustl.edu/washu-investigator-credits-icts-resources-and-funding-on-her-path-to-2-8-million-grant-from-the-national-institutes-of-health-nih/" target="_blank" rel="noopener noreferrer">Read the full article.</a>

Washington University in St. Louis Institute of Clinical and Translational Sciences

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Washington University

WashU Investigator Credits ICTS Resources and Funding on Her Path to $2.8 Million Grant from the NIH 

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