Differences in how young adults metabolize THC, the main part of cannabis that makes people feel “high,” can influence how they feel after taking the drug as well as their potential risk for developing cannabis use disorder, or CUD.
These findings were recently published in Addictive Behaviors by Medical University of South Carolina (MUSC) researcher Rachel Tomko, Ph.D., and former psychology intern Christal Davis, Ph.D., who is now a postdoctoral fellow at the University of Pennsylvania, as well as other MUSC colleagues and collaborators at the University of Florida and University of Colorado. Tomko and Davis also explored whether the effects of a genetic difference in THC metabolism on future outcomes of cannabis use depend on a person’s sex.
CUD, which affects one in five people who use cannabis, leads to problems such as withdrawal symptoms and cravings when not using cannabis, difficulty reducing cannabis use and a need to consume more of the drug to experience the same effects…
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