In a large clinical trial, UT Southwestern Medical Center researchers developed a robust model for testing strategies to prevent health problems in patients with multiple chronic conditions. The study, published in the New England Journal of Medicine, addressed a lack of research on the effectiveness of guideline-directed therapies and included patients from racial groups who are typically underrepresented in clinical trials.
Miguel Vazquez, M.D., Professor of Internal Medicine and Clinical Director of the Division of Nephrology at UT Southwestern, said the trial was notable for taking place under real-world conditions. "We proved that it was possible to conduct a rigorous trial where patients from multiple large health care clinics are receiving care to test interventions for overlapping diseases that can cause serious complications and death," he said.
Dr. Vazquez led the study with Robert Toto, M.D., Professor of Internal Medicine, Director of the Center for Translational Medicine, Medical Director of UT Southwestern’s Multi-Specialty Clinic, and Associate Dean of the UT Southwestern Clinical and Translational Science Award (CTSA) Program…
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