Goal #4: Improve clinical research

Date: Wednesday, May 28, 2025Time: 5:30 p.m. - 6:30 p.m., ETLocation: Zoom&nbsp;The Health System Innovation Award is designed to support the development, implementation, and evaluation of high-priority healthcare interventions that improve access, quality, efficiency, patient-centeredness, and equity in care delivery. Pitch your idea at the kick-off meeting!&nbsp;Eligibility<ul><li>PI must be a USC faculty member</li><li>Co-investigators should include healthcare system personnel</li><li>Teams must include expertise in both research methodology and healthcare system operations</li></ul>Letters of Intent must be submitted by 8 p.m. ET on June 27, 2025&nbsp;Learn more about the Award <a href="https://sites.usc.edu/hdscenter/2025-health-system-innovation-award/" target="_blank" rel="noopener noreferrer">here</a>.Join the Zoom <a href="https://usc.zoom.us/j/7394763330?pwd=ZURaS3Jwcm81WFVzUGkxMlplT0FMQT09&amp;_x_zm_rtaid=RA0Oy7FbSGeMTA4IhMp0-Q.1746643850414.23c04f9aebe7460a8aadab99a04e5fe3&amp;_x_zm_rhtaid=175#success" target="_blank" rel="noopener noreferrer">here</a>.

Southern California Clinical and Translational Science Institute

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University of Southern California

University of Southern California CTSI Health System Innovation Award Kick-off Meeting

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Goal #1: Advance clinical and translational science

The University of Kentucky <a href="https://www.ccts.uky.edu/" target="_blank" rel="noopener noreferrer">Center for Clinical and Translational Science</a> (CCTS) hosted its 20th Annual Spring Conference on April 1, 2025 drawing its largest audience ever—more than 1,150 researchers, clinicians, students, and community members to share findings and foster collaborations. The annual event is a pillar of the CCTS’s mission to accelerate discoveries that improve health. Its agenda featured two renowned keynote speakers, more than 50 podium presentations, 380 poster presentations (including 22 by&nbsp;students from Lexington’s Frederick Douglass High School Biomedical Pathways Program), the Von Allmen Center for Entrepreneurship 60-Second Poster Pitch Competition, and Mentor Recognition Awards…&nbsp;Read the full article <a href="https://www.ccts.uky.edu/news/20th-annual-spring-ccts-conference-largest-ever-1150-participants" target="_blank" rel="noopener noreferrer">here</a>.

Kentucky Center for Clinical and Translational Science

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University of Kentucky

20th Annual Spring CCTS Conference is Largest Ever with 1,150 Participants

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Date: Tuesday, May 20, 2025Time: 12:00 p.m. ETLocation: Zoom&nbsp;Speaker: <a href="https://www.olavoamaral.com/" target="_blank" rel="noopener noreferrer">Professor Olavo Amaral, M.D., Ph.D.</a>, Leopoldo de Meis Institute of Medical Biochemistry, Federal University of Rio de Janeiro&nbsp;&nbsp;In this talk, we will present the results of a large multicenter replication of biomedical lab research from Brazil using three common experimental methods: the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, the reverse transcription polymerase chain reaction (RT-PCR), and the elevated plus maze (EPM) experiments in mice. A total of 56 laboratories performed 143 replications of 56 experiments, of which 97 replications of 47 experiments were judged valid by an independent committee. Replication rates for these experiments varied between 15% and 45% according to five predefined criteria. In median terms, relative effect sizes (expressed as ratios of means) were 60% larger in original experiments than in replications, while coefficients of variation were 60% smaller. Beyond the results, we will discuss what we have learned about factors that limit replicability in lab biology, as well as about the challenges of performing large-scale confirmatory research projects in academia.&nbsp;Learn more about Reproducibility Rounds <a href="https://med.stanford.edu/sporr/education/training/Reproducibility_Rounds.html" target="_blank" rel="noopener noreferrer">here</a>.Register <a href="https://stanford.zoom.us/meeting/register/2lyM5DNWSFuW024mywVbOA#/registration" target="_blank" rel="noopener noreferrer">here</a>.

Stanford Center for Clinical & Translational Education and Research (Spectrum)

Olavo Amaral.avif

Stanford

Reproducibility Rounds: Estimating Replicability of Lab Biology Research at a National Level - Results and Lessons from the Brazilian Reproducibility Initiative

CTSA CCOS

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University of Southern California CTSI Health System Innovation Award Kick-off Meeting