Date/Time: Tuesday, January 21, 2025, 12:00 pm ET
Location: Zoom
Speakers: Timothy M. Errington, Ph.D., M.A., Senior Director of Research, Center for Open Science
The Reproducibility Project: Cancer Biology was a large-scale systematic investigation into the replicability of high-impact, preclinical cancer biology experiments. Overall, there were challenges at every stage of the research process from design to conducting the replications. It was hard to understand what was originally done, there was not always access to the original data or reagents to conduct the experiments, and the model systems frequently did not behave as originally reported. The limited transparency and incomplete reporting made the efforts to replicate the findings much harder than was necessary. Of the replication experiments able to be completed, the evidence was much weaker on average than the original findings even though all the replications underwent peer review before conducting the experiments to maximize their quality and rigor. These findings suggest that there is unnecessary friction in the research process that may be slowing the advancement of knowledge, solutions, and treatments.
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Learn more about Reproducibility Rounds here.
