The Principles for AI Translation in Healthcare (PATH) Working Group is a CTSA-led initiative focused on advancing the responsible, scalable integration of artificial intelligence (AI) into clinical and translational research. Building on national guidance from the Coalition for Health AI (CHAI), the group aims to operationalize principles such as fairness, transparency, and accountability within academic medical centers (AMCs). PATH will develop implementation-ready frameworks, governance strategies, and evaluation systems that support the ethical deployment of AI models in real-world healthcare settings. The group emphasizes multi-institutional collaboration, regulatory alignment, and sustainability to ensure long-term impact across the CTSA network.
Principles for AI Translation in Healthcare

Overview
The Principles for AI Translation in Healthcare (PATH) Working Group is a CTSA-led initiative focused on advancing the responsible, scalable integration of artificial intelligence (AI) into clinical and translational research. Building on national guidance from the Coalition for Health AI (CHAI), the group aims to operationalize principles such as fairness, transparency, and accountability within academic medical centers (AMCs). PATH will develop implementation-ready frameworks, governance strategies, and evaluation systems that support the ethical deployment of AI models in real-world healthcare settings. The group emphasizes multi-institutional collaboration, regulatory alignment, and sustainability to ensure long-term impact across the CTSA network.

Group Goals
Develop a translational AI evaluation framework tailored to the real-world needs of CTSA academic medical centers.
Define standardized evaluation criteria to support fair, generalizable, and transparent AI model assessment across institutions.
Create best practices for deploying validated AI models, including clinician engagement and post-deployment monitoring.
Build a shared infrastructure for federated AI model evaluation across CTSA hubs to support multi-institutional collaboration.
Design a long-term strategy for sustainable AI governance and institutional integration.
Disseminate the group’s outputs through publications, national conferences, and targeted workshops to promote adoption.
Upcoming Meetings
The PATH Working Group meetings are held on the second Wednesday of each month at 3:00 PM ET.
Principles for AI Translation in Healthcare WG - 12/10/2025
Wednesday, December 10, 2025
03:00 PM - 04:00 PM EST
Principles for AI Translation in Healthcare WG - 12/10/2025
Wednesday, December 10, 2025
03:00 PM - 04:00 PM EST
Upcoming Meetings
The PATH Working Group meetings are held on the second Wednesday of each month at 3:00 PM ET.
Contact Information
For more information or to join the PATH Working Group, please contact the CCOS coordinator.
Contact Information
For more information or to join the PATH Working Group, please contact the CCOS coordinator.



